Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

BACKGROUND: In Caenorhabditis elegans, injection of double-stranded RNA (dsRNA) results in the specific inactivation of genes containing homologous sequences, a technique termed RNA-mediated interference (RNAi). It has previously been shown that RNAi can also be achieved by feeding worms Escherichia...

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Main Authors: Kamath, Ravi S, Martinez-Campos, Maruxa, Zipperlen, Peder, Fraser, Andrew G, Ahringer, Julie
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2001
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC17598/
https://ncbi.nlm.nih.gov/pubmed/11178279
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