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Temocillin efficacy in experimental Klebsiella pneumoniae meningitis after infusion into rabbit plasma to simulate antibiotic concentrations in human serum.

An infusion system was developed to simulate in the plasma of rabbits the concentrations of temocillin in human serum measured after administration of a 2-g intravenous bolus dose. The efficacy of therapy with this infusion against experimental Klebsiella pneumoniae meningitis was compared with that...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Woodnutt, G, Catherall, E J, Kernutt, I, Mizen, L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3252752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.11.1705
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