Pharmacokinetics and metabolism of rimantadine hydrochloride in mice and dogs.

We studied the pharmacokinetics and metabolism of rimantadine hydrochloride (rimantadine) following single-dose oral and intravenous administration in mice and dogs. Absorption of the compound in mice was rapid. Maximum concentrations in plasma occurred at less than 0.5 h after oral administration,...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hoffman, H E, Gaylord, J C, Blasecki, J W, Shalaby, L M, Whitney, C C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175954/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3252751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.11.1699
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