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Relationships between renal function and disposition of oral ciprofloxacin.

The relationships between creatinine clearance (CLCR) and the pharmacokinetics of oral ciprofloxacin were characterized. On the basis of these data, a dosage adjustment strategy, which incorporates the severity of infection and the size and renal function of the patient, was developed. An adaptive (...

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Библиографические подробности
Опубликовано в::Antimicrob Agents Chemother
Главные авторы: Forrest, A, Weir, M, Plaisance, K I, Drusano, G L, Leslie, J, Standiford, H C
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1988
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3190182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.10.1537
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