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Isolation, characterization, and cloning of a plasmid-borne gene encoding a phosphotransferase that confers high-level amikacin resistance in enteric bacilli.

Clinical isolates of Klebsiella pneumoniae and Serratia marcescens at a hospital that had used amikacin as its principal aminoglycoside for the preceding 42 months demonstrated high-level resistance to amikacin (greater than or equal to 256 micrograms/ml), kanamycin (greater than or equal to 256 mic...

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Gaynes, R, Groisman, E, Nelson, E, Casadaban, M, Lerner, S A
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175872/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2848443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.9.1379
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