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Enhancement of leukotriene B4 release in stimulated asthmatic neutrophils by platelet activating factor

BACKGROUND: The role of platelet activating factor (PAF) in asthma remains controversial. The priming effect of PAF on leukotriene B4 (LTB4) release, 5-lipoxygenase activity, and intracellular calcium levels in asthmatic neutrophils was examined. METHODS: LTB4 and other lipoxygenase metabolites in n...

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Detalhes bibliográficos
Main Authors: Shindo, K., Koide, K., Fukumura, M.
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1758460/
https://ncbi.nlm.nih.gov/pubmed/9516893
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