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Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma

BACKGROUND: There are two isoforms of cyclo-oxygenase (COX), namely COX- 1 and COX-2. COX-1 is constitutively expressed in most tissues and in blood platelets. The metabolites derived from COX-1 are probably involved in cellular housekeeping functions. COX-2 is expressed only following cellular acti...

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Bibliographische Detailangaben
Hauptverfasser: Sousa, A., Pfister, R., Christie, P. E., Lane, S. J., Nasser, S. M., Schmitz-Schumann, M., Lee, T. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1758450/
https://ncbi.nlm.nih.gov/pubmed/9487340
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