Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms.

The macrolide antibiotic azithromycin (CP-62,993; 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A; also designated XZ-450 [Pliva Pharmaceuticals, Zagreb, Yugoslavia]) showed a significant improvement in potency against gram-negative organisms compared with erythromycin while retaining the classic ery...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Retsema, J, Girard, A, Schelkly, W, Manousos, M, Anderson, M, Bright, G, Borovoy, R, Brennan, L, Mason, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2449865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.12.1939
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