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Formulation, toxicity, and antifungal activity in vitro of liposome-encapsulated nystatin as therapeutic agent for systemic candidiasis.

Multilamellar vesicles containing nystatin (NYS) were compared with vesicles containing the free drug for toxicity to erythrocytes and for antifungal activity in vitro. Liposomal nystatin was as active as free NYS was against a wide variety of yeasts and fungi. The antifungal activity against Candid...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Mehta, R T, Hopfer, R L, Gunner, L A, Juliano, R L, Lopez-Berestein, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3439798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.12.1897
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