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Cancer dormancy and cell signaling: Induction of p21(waf1) initiated by membrane IgM engagement increases survival of B lymphoma cells

The p21(WAF1) (p21) cyclin-dependent kinase inhibitor plays a major role in regulating cell cycle arrest. It was recently reported that the p53-independent elevation of p21 protein levels is essential in mediating the G(1) arrest resulting from signal transduction events initiated by the crosslinkin...

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Библиографические подробности
Главные авторы: Marches, Radu, Hsueh, Robert, Uhr, Jonathan W.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1999
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC17581/
https://ncbi.nlm.nih.gov/pubmed/10411940
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