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Immunogenicity and protective efficacy of the alpha C protein of group B streptococci are inversely related to the number of repeats.

Infection by group B streptococci (GBS) is an important cause of bacterial disease in neonates. Alpha C protein is a protective cell surface-associated protein of GBS. This protein contains a repeat region flanked by N and C termini. Variable expression of tandem repeating units of alpha C proteins...

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Published in:Infect Immun
Main Authors: Gravekamp, C, Kasper, D L, Michel, J L, Kling, D E, Carey, V, Madoff, L C
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175751/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9393818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.12.5216-5221.1997
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