The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages.

Shigella, the etiological agent of bacillary dysentery, rapidly kills human monocyte-derived macrophages in vitro. Wild-type Shigella flexneri, but not a nonvirulent derivative, induced human macrophage apoptosis as determined by morphology and terminal deoxynucleotidyltransferase-mediated dUTP-biot...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Hilbi, H, Chen, Y, Thirumalai, K, Zychlinsky, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9393811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.12.5165-5170.1997
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