Escherichia coli cytolethal distending toxin blocks the HeLa cell cycle at the G2/M transition by preventing cdc2 protein kinase dephosphorylation and activation.

Cytolethal distending toxins (CDT) constitute an emerging heterogeneous family of bacterial toxins whose common biological property is to inhibit the proliferation of cells in culture by blocking their cycle at G2/M phase. In this study, we investigated the molecular mechanisms underlying the block...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Comayras, C, Tasca, C, Pérès, S Y, Ducommun, B, Oswald, E, De Rycke, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9393800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.12.5088-5095.1997
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