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Protection against Pneumocystis carinii pneumonia by antibodies generated from either T helper 1 or T helper 2 responses.

To determine whether different antibody isotypes associated with T helper 1 (Th1) or Th2 responses are protective against Pneumocystis carinii, mice with disrupted interleukin 4 genes (IL-4(-/-) mice) or gamma interferon genes (IFN-gamma(-/-) mice) along with wild-type C57BL/6 mice were immunized in...

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Bibliographic Details
Main Authors: Garvy, B A, Wiley, J A, Gigliotti, F, Harmsen, A G
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC175728/
https://ncbi.nlm.nih.gov/pubmed/9393795
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