The acylated form of protein D of Haemophilus influenzae is more immunogenic than the nonacylated form and elicits an adjuvant effect when it is used as a carrier conjugated to polyribosyl ribitol phosphate.

The nonacylated form of protein D (PDm) of Haemophilus influenzae has been shown to induce the production of antibodies that are bactericidal to homologous and heterologous nontypeable H. influenzae (NTHi) strains. In this study, immunization of rats with lipoprotein D (LPD) induced higher levels of...

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Pubblicato in:	Infect Immun
Autori principali:	Akkoyunlu, M, Melhus, A, Capiau, C, van Opstal, O, Forsgren, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9393790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.12.5010-5016.1997
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