Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection.

Chronic infection of the gastroduodenal mucosae by the gram-negative spiral bacterium Helicobacter pylori is responsible for chronic active gastritis, peptic ulcers, and gastric cancers such as adenocarcinoma and low-grade gastric B-cell lymphoma. The success of eradication by antibiotic therapy is...

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Main Authors: Ghiara, P, Rossi, M, Marchetti, M, Di Tommaso, A, Vindigni, C, Ciampolini, F, Covacci, A, Telford, J L, De Magistris, M T, Pizza, M, Rappuoli, R, Del Giudice, G
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC175721/
https://ncbi.nlm.nih.gov/pubmed/9393788
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