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Confounding by indication in non-experimental evaluation of vaccine effectiveness: the example of prevention of influenza complications

Randomised allocation of vaccine or placebo is the preferred method to assess the effects of the vaccine on clinical outcomes relevant to the individual patient. In the absence of phase 3 trials using clinical end points, notably post-influenza complications, alternative non-experimental designs to...

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Detalhes bibliográficos
Main Authors: Hak, E, Verheij, T., Grobbee, D, Nichol, K, Hoes, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1756997/
https://ncbi.nlm.nih.gov/pubmed/12461118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jech.56.12.951
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