The cytoplasmic membrane is a primary target for the staphylocidal action of thrombin-induced platelet microbicidal protein.

Thrombin-induced platelet microbicidal protein (tPMP-1) is a small, cationic peptide released from rabbit platelets exposed to thrombin in vitro. tPMP-1 is microbicidal against a broad spectrum of bloodstream pathogens, including Staphylococcus aureus. Preliminary evidence suggests that tPMP-1 targe...

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Pubblicato in:	Infect Immun
Autori principali:	Koo, S P, Yeaman, M R, Nast, C C, Bayer, A S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9353067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.11.4795-4800.1997
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