Hyperproduction of alpha-toxin by Staphylococcus aureus results in paradoxically reduced virulence in experimental endocarditis: a host defense role for platelet microbicidal proteins.

Staphylococcal alpha-toxin targets several cell types which are important components of cardiac vegetations in endocarditis, including platelets, erythrocytes, and endothelial cells. We evaluated the in vivo role of Staphylococcus aureus alpha-toxin in experimental endocarditis by using isogenic str...

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Pubblicato in:	Infect Immun
Autori principali:	Bayer, A S, Ramos, M D, Menzies, B E, Yeaman, M R, Shen, A J, Cheung, A L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9353046/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.11.4652-4660.1997
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