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The lack of consensus for I-A(g7)-peptide binding motifs: Is there a requirement for anchor amino acid side chains?

We discuss here the problems in identifying sequence motifs of peptides that bind to I-A(g7), the class II histocompatibility molecule of NOD diabetic mice. We present studies that indicate a minor contribution of amino acid side chains for binding. A peptide from the Eα chain binds to I-A(g7) molec...

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Detalhes bibliográficos
Main Authors: Carrasco-Marin, Eugenio, Kanagawa, Osami, Unanue, Emil R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17566/
https://ncbi.nlm.nih.gov/pubmed/10411925
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