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Interleukin-12 is indispensable for protective immunity against Leishmania major.

Interleukin-12 (IL-12)-deficient mice derived from a strain genetically resistant to infection with Leishmania major were recently shown to be susceptible toward this parasite, developing a strong Th2 response after injection of a large number of parasites. We further investigated the role of IL-12...

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Bibliographic Details
Main Authors: Mattner, F, Di Padova, K, Alber, G
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC175629/
https://ncbi.nlm.nih.gov/pubmed/9353008
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