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Phosphatase-1 and -2A inhibition modulates apoptosis in human osteoarthritis chondrocytes independently of nitric oxide production

Methods: Human OA chondrocytes were isolated from cartilage obtained from the femoral heads of patients undergoing joint replacement surgery. Cell viability was evaluated by MTT assay. Apoptosis was quantified by ELISA, which measures DNA fragmentation. Nitric oxide (NO) production was evaluated by...

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Detalhes bibliográficos
Principais autores: Lopez-Armada, M, Carames, B, Cillero-Pastor, B, Lires-Dean, M, Maneiro, E, Fuentes, I, Ruiz, C, Galdo, F, Blanco, F
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755582/
https://ncbi.nlm.nih.gov/pubmed/15958763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.034090
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