Depletion of synovial macrophages in rheumatoid arthritis by an anti-FcγRI-calicheamicin immunoconjugate

Background: Monocytes/macrophages have an important and versatile role in joint inflammation and destruction in rheumatoid arthritis (RA). Objective: To determine the efficiency of monocyte/macrophage elimination by a new drug conjugated antibody (CD64-calicheamicin (CD64-CaMi)) directed to the high...

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Bibliographic Details
Main Authors: van Roon, J A G, Bijlsma, J, van de Winkel, J G J, Lafeber, F
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Extended Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755535/
https://ncbi.nlm.nih.gov/pubmed/15539412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.028845
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