Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection.

A distinguishing feature of Pseudomonas aeruginosa isolates from cystic fibrosis (CF) patients is their mucoid, exopolysaccharide alginate-overproducing phenotype. One mechanism of conversion to mucoidy is based on mutations in the algU mucABCD cluster, encoding the stress sigma factor AlgU and its...

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Pubblicato in:	Infect Immun
Autori principali:	Boucher, J C, Yu, H, Mudd, M H, Deretic, V
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.9.3838-3846.1997
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