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Toll-like receptor 4 gene polymorphisms and susceptibility to juvenile idiopathic arthritis

Methods: 313 simplex families (each containing one affected JIA proband) were genotyped. Two known functionally important single nucleotide polymorphisms (SNPs) within the TLR4 gene (Asp299Gly and Thr399Ile) were typed by SNaPshot ddNTP primer extension and capillary electrophoresis. Single point an...

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Main Authors: Lamb, R, Zeggini, E, Thomson, W, BSPAR, Donn, R
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755476/
https://ncbi.nlm.nih.gov/pubmed/15498795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.026930
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