Increased circulating levels of tissue kallikrein in systemic sclerosis correlate with microvascular involvement

Background: In systemic sclerosis (SSc) the lack of an angiogenic response to hypoxia may be due to inappropriate synthesis of angiogenic and angiostatic factors. Tissue kallikrein (t-kallikrein), regulating the kallikrein-kinin system and acting on the microcirculation, is a potent angiogenic agent...

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Detalhes bibliográficos
Main Authors: Del Rosso, A, Distler, O, Milia, A, Emanueli, C, Ibba-Manneschi, L, Guiducci, S, Conforti, M, Generini, S, Pignone, A, Gay, S, Madeddu, P, Matucci-Cerinic, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755411/
https://ncbi.nlm.nih.gov/pubmed/15708892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.023382
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