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Pathogenic role of anti-ß2-glycoprotein I antibodies in antiphospholipid associated fetal loss: characterisation of ß2-glycoprotein I binding to trophoblast cells and functional effects of anti-ß2-glycoprotein I antibodies in vitro

Background: Antiphospholipid antibodies reacting with ß2-glycoprotein I (ß2GPI) have been associated with recurrent fetal loss and pregnancy complications. Objective: To investigate whether specific mutations in the phospholipid binding site of ß2GPI might affect its binding to trophoblast and in tu...

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Main Authors: Di, S, Raschi, E, Testoni, C, Castellani, R, D'Asta, M, Shi, T, Krilis, S, Caruso, A, Meroni, P
פורמט: Artigo
שפה:Inglês
יצא לאור: 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755387/
https://ncbi.nlm.nih.gov/pubmed/15256379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.021444
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