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Increased Bcl-2/p53 ratio in human osteoarthritic cartilage: a possible role in regulation of chondrocyte metabolism

Objective: To determine whether Bcl-2, p53, and Fas/CD95 help to control cartilage metabolism. Methods: Six normal and 14 osteoarthritic (OA) cartilage samples were examined, and two zones from each sample showing the least (Min) and most (Max) anatomical damage were selected. Chondrocytes were isol...

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Detalhes bibliográficos
Main Authors: Iannone, F, De Bari, C, Scioscia, C, Patella, V, Lapadula, G
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755345/
https://ncbi.nlm.nih.gov/pubmed/15647429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.022590
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