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Extranuclear detection of histones and nucleosomes in activated human lymphoblasts as an early event in apoptosis

Objective: To evaluate the presence of histones and nucleosomes in cell lysates of freshly isolated peripheral blood mononuclear cells (PBMC), fully activated lymphoblasts, or lymphoblasts after induction of apoptosis. Methods: Each histone class (H1, H2A, H2B, H3, and H4) was detected by western bl...

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Autors principals: Gabler, C, Blank, N, Hieronymus, T, Schiller, M, Berden, J, Kalden, J, Lorenz, H
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755110/
https://ncbi.nlm.nih.gov/pubmed/15308524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.011452
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