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Leflunomide inhibits transendothelial migration of peripheral blood mononuclear cells
Objectives: To test whether the active metabolite of leflunomide (LEF-M), in addition to blocking the proliferation of activated lymphocytes by inhibiting dihydro-orotate dehydrogenase (DHODH), influences the transendothelial migration (TEM) of peripheral blood mononuclear cells (PBMC). Methods: In...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1754829/ https://ncbi.nlm.nih.gov/pubmed/15547088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.018440 |
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