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Anti-CD4 monoclonal antibody treatment in acute and early chronic antigen induced arthritis: influence on macrophage activation

Objective: To investigate the indirect effects of anti-CD4 treatment on the functions of macrophages (CD4(–) in mice) in the acute and early chronic phase of mouse antigen induced arthritis (AIA). Methods: C57BL/6 mice with AIA were treated intraperitoneally with the anti-CD4 mAb GK1.5 or control ra...

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Detalhes bibliográficos
Main Authors: Nissler, K, Pohlers, D, Huckel, M, Simon, J, Brauer, R, Kinne, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754787/
https://ncbi.nlm.nih.gov/pubmed/15479897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.013060
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