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EP(2)/EP(4) signalling inhibits monocyte chemoattractant protein-1 production induced by interleukin 1ß in synovial fibroblasts

Background: Besides its proinflammatory properties, prostaglandin E(2) (PGE(2)) acts as a regulator of the expression of inducible genes. Inhibition of PGE(2) synthesis might thus result in a paradoxical deleterious effect on inflammation. Objective: To examine the effect of PGE(2) on monocyte chemo...

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Detalhes bibliográficos
Main Authors: Largo, R, Diez-Ortego, I, Sanchez-Pernaute, O, Lopez-Armada, M, Alvarez-Soria, M, Egido, J, Herrero-Beaumont, G
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754778/
https://ncbi.nlm.nih.gov/pubmed/15361371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.011163
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