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Metabolic activation stimulates acid secretion and expression of matrix degrading proteases in human osteoblasts

Background: Both cellular and matrix components of healthy bone are permanently renewed in a balanced homoeostasis. Osteoclastic bone resorption involves the expression of vacuolar-type ATPase proton pumps (vATPase) on the outer cell membrane and the secretion of matrix degrading proteases. Osteobla...

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Detalhes bibliográficos
Main Authors: George, M, Stein, B, Muller, O, Weis-Klemm, M, Pap, T, Parak, W, Aicher, W
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754733/
https://ncbi.nlm.nih.gov/pubmed/14672894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2002.005256
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