Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FcγRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE

Background: Raised interleukin (IL)6 and IL10 levels are thought to contribute to the pathogenesis of systemic lupus erythematosus (SLE) by enhancing autoantibody production and immune complex (IC) formation. These immune complexes can then stimulate cellular reactions through Fc and complement rece...

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Bibliographic Details
Main Authors: Ronnelid, J, Tejde, A, Mathsson, L, Nilsson-Ekdahl, K, Nilsson, B
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Extended Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754302/
https://ncbi.nlm.nih.gov/pubmed/12480667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.62.1.37
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