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Time between onset of apoptosis and release of nucleosomes from apoptotic cells: putative implications for systemic lupus erythematosus

Objective: To investigate the kinetics of nucleosome leakage from apoptotic cells in an in vitro system and extrapolate the results to autoimmune disease, in particular systemic lupus erythematosus. Methods: A sensitive nucleosome enzyme linked immunosorbent assay (ELISA) was developed, using a mono...

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Detalhes bibliográficos
Main Authors: van Nieuwenhuijze, A E M, van Lopik, T, Smeenk, R, Aarden, L
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754285/
https://ncbi.nlm.nih.gov/pubmed/12480662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.62.1.10
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