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Differential expression patterns of matrix metalloproteinases and their inhibitors during development of osteoarthritis in a transgenic mouse model

Objective: To characterise the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) during degeneration of articular cartilage in a transgenic Del1 mouse model for osteoarthritis. Methods: Northern analysis was used to measure mRNA levels of MMP-2, -3, -...

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Detalhes bibliográficos
Main Authors: Salminen, H, Saamanen, A, Vankemmelbeke, M, Auho, P, Perala, M, Vuorio, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754156/
https://ncbi.nlm.nih.gov/pubmed/12079898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.61.7.591
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