A synthetic lipopolysaccharide-binding peptide based on the neutrophil-derived protein CAP37 prevents endotoxin-induced responses in conscious rats.

The lipid A component of lipopolysaccharide (LPS) derived from Escherichia coli has been implicated as a significant mediator in the development of circulatory and metabolic dysfunction and lethality associated with sepsis. A synthetic peptide corresponding to amino acid residues 20 through 44 of th...

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Publié dans:	Infect Immun
Auteurs principaux:	Brackett, D J, Lerner, M R, Lacquement, M A, He, R, Pereira, H A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.7.2803-2811.1997
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