Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina.

Forty-five volunteers were vaccinated twice intranasally with 10, 100, or 1,000 microg of cholera toxin B subunit (CTB). Blood and nasal and vaginal secretions were collected before and 1 week after the second vaccination from all volunteers, and the specific and total immunoglobulin A (IgA) and IgG...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Bergquist, C, Johansson, E L, Lagergård, T, Holmgren, J, Rudin, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199436/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.7.2676-2684.1997
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!