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Analysis of the cell infiltrate and expression of matrix metalloproteinases and granzyme B in paired synovial biopsy specimens from the cartilage-pannus junction in patients with RA

OBJECTIVES—Examination of synovial tissue (ST) obtained at surgery because of end stage destructive rheumatoid arthritis (RA) showed that macrophages and fibroblasts are the major cell types at the cartilage-pannus junction (CPJ). This study aimed at defining the cell infiltrate and mediators of joi...

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Autores principales: Smeets, T, Kraan, M, Galjaard, S, Youssef, P, Smith, M, Tak, P
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753677/
https://ncbi.nlm.nih.gov/pubmed/11350843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.6.561
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