Intrapulmonary response to Histoplasma capsulatum in gamma interferon knockout mice.

We examined the immunobiological responses to Histoplasma capsulatum in lungs of gamma interferon (IFN-gamma) knockout mice (GKO mice). Naive GKO mice succumbed by day 9 to intranasal challenge with 2.5 x 10(6) yeasts, whereas all wild-type (WT) mice survived for 45 days. Compared to lungs of WT mic...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Allendoerfer, R, Deepe, G S
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199420/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.7.2564-2569.1997
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