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The tumor necrosis factor alpha-stimulating region of galactose-inhibitable lectin of Entamoeba histolytica activates gamma interferon-primed macrophages for amebicidal activity mediated by nitric oxide.

Entamoeba histolytica adheres via galactose-lectin (Gal-lectin) to human colonic mucins and intestinal epithelial cells as a prerequisite to amebic invasion. Native Gal-lectin is a protective antigen in the gerbil model of amebiasis. Amino acids 596 to 1082 of Gal-lectin mediate E. histolytica adher...

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Bibliografiska uppgifter
I publikationen:Infect Immun
Huvudupphov: Séguin, R, Mann, B J, Keller, K, Chadee, K
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.7.2522-2527.1997
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