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Amyloidosis induced, end stage renal disease in patients with familial Mediterranean fever is highly associated with point mutations in the MEFV gene

BACKGROUND—Familial Mediterranean fever (FMF) is an autosomal recessive disease characterised by recurrent attacks of fever and serositis. Amyloidosis is the most significant complication of FMF, leading to end stage renal disease (ESRD). Recently the gene (MEFV) causing this disease was cloned and...

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Detalhes bibliográficos
Principais autores: Ben-Chetrit, E, Backenroth, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753463/
https://ncbi.nlm.nih.gov/pubmed/11156548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.2.146
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