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Relation between adverse events associated with allopurinol and renal function in patients with gout

BACKGROUND—Because serious adverse reactions to allopurinol have been related to a reduce creatinine clearance rate and prolonged half life of oxypurinol, it has been recommended that the dose should be adjusted according to the rate of creatinine clearance. However, in some patients with gout the d...

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Autors principals: Vazquez-Mellado, J, Morales, E, Pacheco-Tena, C, Burgos-Vargas, R
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753376/
https://ncbi.nlm.nih.gov/pubmed/11557658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.10.981
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