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Low T cell production of TNFα and IFNγ in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism

OBJECTIVE—To test the hypothesis that ankylosing spondylitis (AS) is a T helper cell type 2 polarised disease by quantifying the T cell cytokines interferon γ (IFNγ), interleukin 4 (IL4), tumour necrosis factor α (TNFα), and IL10 at the single cell level in patients with AS in comparison with health...

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Detalhes bibliográficos
Main Authors: Rudwaleit, M, Siegert, S, Yin, Z, Eick, J, Thiel, A, Radbruch, A, Sieper, J, Braun, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753353/
https://ncbi.nlm.nih.gov/pubmed/11114280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.1.36
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