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Spontaneous and cytokine regulated c-fos gene expression in rheumatoid synovial cells: resistance to cytokine stimulation when the c-fos gene is overexpressed

OBJECTIVE—To study the effect of cytokines on the transactivation of the c-fos gene in relation to the contribution of overexpression of c-fos/AP-1 in rheumatoid joint destruction.
METHODS—The promoter region (−447 to +109) of the human c-fos gene was integrated upstream of the chloramphenicol acety...

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Bibliografske podrobnosti
Main Authors: Shimizu, K, Kawasaki, H, Morisawa, T, Nakamura, M, Yamamoto, E, Yoshikawa, N, Doita, M, Shiozawa, K, Yonehara, S, Chihara, K, Shiozawa, S
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753200/
https://ncbi.nlm.nih.gov/pubmed/10913062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.8.636
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