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Spontaneous and cytokine regulated c-fos gene expression in rheumatoid synovial cells: resistance to cytokine stimulation when the c-fos gene is overexpressed
OBJECTIVE—To study the effect of cytokines on the transactivation of the c-fos gene in relation to the contribution of overexpression of c-fos/AP-1 in rheumatoid joint destruction. METHODS—The promoter region (−447 to +109) of the human c-fos gene was integrated upstream of the chloramphenicol acety...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1753200/ https://ncbi.nlm.nih.gov/pubmed/10913062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.8.636 |
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