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Decreased T cell precursor frequencies to Epstein-Barr virus glycoprotein gp110 in peripheral blood correlate with disease activity and severity in patients with rheumatoid arthritis

OBJECTIVES—Rheumatoid arthritis (RA) is a chronic joint disease associated with certain HLA-DR alleles expressing the QK/RRAA motif or shared epitope. The Epstein-Barr virus (EBV) has been suspected to be a causative factor for RA. The EBV gp110, a glycoprotein of the replicative cycle that contains...

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Autori principali: Toussirot, E., Wendling, D., Tiberghien, P., Luka, J., Roudier, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753187/
https://ncbi.nlm.nih.gov/pubmed/10873963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.7.533
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