Temperature-sensitive mutants of Actinobacillus pleuropneumoniae induce protection in mice.

Temperature-sensitive mutants of Actinobacillus pleuropneumoniae 4074, serotype 1, were isolated after treatment with nitrosoguanidine and enrichment with penicillin and D-cycloserine. Of the four temperature-sensitive mutants evaluated in mice, one (A-1) had a tight phenotype (i.e., it ceased repli...

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Bibliographic Details
Main Authors: Byrd, W, Hooke, A M
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC175304/
https://ncbi.nlm.nih.gov/pubmed/9169752
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