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Effect of thrombin inhibition on synovial inflammation in antigen induced arthritis
OBJECTIVE—To determine the effect of the thrombin inhibitor, hirudin, on the pathogenesis of murine antigen induced arthritis (AIA). METHODS—AIA was induced by intra-articular injection of methylated bovine serum albumin in the knee joints of previously immunised mice. Hirudin (injected subcutaneous...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1753002/ https://ncbi.nlm.nih.gov/pubmed/11005778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.10.781 |
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