Construction and characterization of a live attenuated vaccine candidate against Shigella dysenteriae type 1.

Vaccine candidates against Shigella dysenteriae type 1, which is associated with the most severe cases of bacillary dysentery, were constructed. The rfp and rfb gene clusters, which code for S. dysenteriae 1 O antigen biosynthesis, were randomly integrated into either the chromosome or the virulence...

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Pubblicato in:	Infect Immun
Autori principali:	Klee, S R, Tzschaschel, B D, Fält, I, Kärnell, A, Lindberg, A A, Timmis, K N, Guzmán, C A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2112-2118.1997
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