Type II collagen is a target antigen of clonally expanded T cells in the synovium of patients with rheumatoid arthritis

OBJECTIVE—To investigate whether type II collagen (CII) is recognised by oligoclonally expanded synovial T cells of patients with rheumatoid arthritis (RA).
METHODS—Peripheral blood mononuclear cells (PBMC) from 15 RA patients were stimulated with CII in vitro. T cell clones expanded by such stimula...

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Autores principales: Sekine, T., Kato, T., Masuko-Hongo, K., Nakamura, H., Yoshino, S., Nishioka, K., Yamamoto, K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Concise Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752913/
https://ncbi.nlm.nih.gov/pubmed/10381490
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